PRK1 (phospho-Thr774) /PRK2 (phospho-Thr816) Rabbit Polyclonal Antibody - RA29009

PRK1 (phospho-Thr774) /PRK2 (phospho-Thr816) Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29009-50, RA29009-100

Citations, Manuals and MSDS Available upon request.

Background: protein kinase N1 (PKN1) Homo sapiens The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:1000-2000

Alternative Names: Serine/threonine-protein kinase N1 (EC 2.7.11.13) (Protease-activated kinase 1) (PAK-1) (Protein kinase C-like 1) (Protein kinase C-like PKN) (Protein kinase PKN-alpha) (Protein-kinase C-related kinase 1) (Serine-threonine protein kinase N)

Applications: WB

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5585

Protein MW (KDa): 103

SWISS: Q16512

Source: Rabbit

Research Use Only