Product Description

PRKX Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5865-50, BS5865-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regμlating a broad range of cellμlar functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. PRKY (protein kinase, Y-linked) and PRKX (protein kinase, X-linked) are members of the Ser/Thr protein kinase family, both of which belong to the subfamily of cAMP-dependent kinases. Encoded by a gene that is located near the pseudoautosomal region on chromosome Y, PRKY contains one protein kinase domain through which it catalyzes the ATP-dependent phosphorylation of target proteins. Functioning in a similar manner to PRXY, PRKX contains one protein kinase domain and is essential for macrophage differentiation and renal epithelial cell migration. Defects in the genes encoding PRKY and PRXX are associated with sex reversal disorder, namely XX in males and XY in females.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: cAMP-dependent protein kinase catalytic subunit PRKX, PrKX, Protein kinase X, Protein kinase X-linked, Serine/threonine-protein kinase PRKX, Protein kinase PKX1, PKX1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 308-353 of Human PRKX.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PRKX polyclonal antibody detects endogenous levels of PRKX protein.

Molecular Weight: ~ 41 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P51817

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only