PRMT6 Mouse Monoclonal Antibody - RA11896

PRMT6 Mouse Monoclonal Antibody

Size: 50μL, 100μL

Catalogue Numbers: RA11896-50, RA11896-100

Citations, Manuals and MSDS Available upon request.

Background: protein arginine methyltransferase 6 (PRMT6) Homo sapiens The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. [provided by RefSeq, Sep 2011],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Applications: WB; IHC; ICC

Species Cross-Reactivity: Human

GeneID (Human): 55170

Protein MW (KDa): 42

SWISS: Q96LA8

Source: Mouse

Research Use Only