Probetacellulin Polyclonal Antibody - BT-AP07405

Probetacellulin Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07405-20, BT-AP07405-50, BT-AP07405-100

Citations, Manuals and MSDS Available upon request.

Background: BTC encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of betacellulin bind to multiple different EGF receptors. Betacellulin romotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in BTC may be associated with type 2 diabetes in human patients.

Research Areas: Signal Transduction

Target Protein: BTC

Applications: WB, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Probetacellulin Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 19746

UniProt Accession: Human: P35070; Mouse: Q05928

Synonyms: BTC; Probetacellulin

GeneID: Human: 685

Research Use Only