Product Description

Profilin 1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10363-50, MB10363-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P07737

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 15 kDa; Observed MW: 15 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Profilin 1 in A549 using Profilin 1 antibody, and DAPI., Western blot analysis of Profilin 1 in C6, 3T3, Hela lysates using Profilin 1 antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsil using Profilin 1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: Epididymis tissue protein Li 184a; Profilin I

Immunogen: A synthetic peptide of human Profilin 1

Conjugate: Unconjugated

Modification: Unmodified