Prostaglandin D Synthase Monoclonal Antibody-MB11461

Prostaglandin D Synthase Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11461-50, MB11461-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P41222

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-Tis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 21 kDa; Observed MW: 26 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Prostaglandin D Synthase in K562 using Prostaglandin D Synthase antibody, and DAPI., Western blot analysis of Prostaglandin D Synthase in K562, C6, 3T3, Hela lysates using Prostaglandin D Synthase antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using Prostaglandin D Synthase antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS

Immunogen: A synthetic peptide of human Prostaglandin D Synthase

Conjugate: Unconjugated

Modification: Unmodified