Proteasome alpha 6 Monoclonal Antibody-MB11465

Proteasome alpha 6 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11465-50, MB11465-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P60900

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome. [provided by RefSeq, Aug 2013]

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 27 kDa; Observed MW: 27 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Proteasome subunit alpha type 6 in K562, C6, 3T3, Hela lysates using Proteasome alpha 6 antibody., Immunocytochemistry analysis of Proteasome subunit alpha type 6 in Hela using Proteasome subunit alpha type 6 antibody, and DAPI

Alternative Name: proteasome subunit alpha 6; IOTA; p27K; PROS27

Immunogen: A synthetic peptide of human Proteasome subunit alpha type 6

Conjugate: Unconjugated

Modification: Unmodified