Product Description

Prothrombin Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA29024-50, RA29024-100

Citations, Manuals and MSDS Available upon request.

Background: coagulation factor II, thrombin (F2) Homo sapiens Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 lead to various forms of thrombosis and dysprothrombinemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: F2; Prothrombin; Coagulation factor II

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 2147

Protein MW (KDa): 70

SWISS: P00734

Source: Rabbit

Research Use Only