Product Description

PRS6A Polyclonal Antibody

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Catalogue Numbers: BS65318-50, BS65318-100

Sizes: 50µl, 100µl

Swiss-Prot: P17980

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,IHC-p,If (paraffin section),ELISA

Background: proteasome 26S subunit, ATPase 3(PSMC3) Homo sapiens The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases that have chaperone-like activity. This subunit may compete with PSMC2 for bindi

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: PSMC3 Polyclonal Antibody detects endogenous levels of PSMC3 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of lysates from K562 and HT-29 cells, using PRS6A Antibody. The lane on the right is blocked with the synthesized peptide., Western blot analysis of the lysates from HT-29 cells using PRS6A antibody.

Bioworld Molecular Weight: ~ 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: PSMC3; TBP1; 26S protease regulatory subunit 6A; 26S proteasome AAA-ATPase subunit RPT5; Proteasome 26S subunit ATPase 3; Proteasome subunit P50; Tat-binding protein 1; TBP-1

Immunogen: The antiserum was produced against synthesized peptide derived from human PRS6A. AA range:271-320

Conjugate: Unconjugated

Modification: Unmodified