PSA Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS91121-50, BS91121-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P07288(Human)
Host: Rabbit
Reactivity: Human
Applications: WB, ICC/IF, IHC
All Applications: WB:1:1,000
ICC:1:50-1:200
IHC:1:50-1:200
Background: Prostate specific antigen (PSA), also designated γ-seminoprotein, seminin, p30 antigen, semenogelase, and kallikrein 3 (KLK3), was first identified as a glycoprotein in human seminal plasma. PSA was determined by sequence similarity to be a member of the kallikrein subfamily of trypsin proteases. PSA is a serine protease that hydrolyzes the major human seminal protein, the seminal plasma mobility inhibitor precursor, or semenogelin I (SPMIP or SgI), which leads to semen liquification. PSA production and expression are highest in normal, benign hyperplastic and cancerous tissues of the prostate, although PSA has also been detected in accessory male sex glands and in breast cancer. PSA has been identified as an aid in the early detection of prostate cancer and is a commonly used tumor marker.
Purification and Purity: ProA affinity purified
Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: PSA polyclonal antibody detects endogenous levels of PSA protein.
Bioworld Molecular Weight: 34 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: ICC staining PSA in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS., Immunohistochemical analysis of paraffin-embedded mouse prostate tissue using anti-PSA antibody. Counter stained with hematoxylin.
Alternative Name: PSA, Seminin, KLK3, antigen, prostate-specific, APS, Gamma seminoprotein, Gamma-seminoprotein, hK3, Kallikrein 3, Kallikrein related peptidase 3, Kallikrein-3, KLK 3, KLK2A1, Klk3, KLK3, P-30 antigen, P30 antigen, Prostate-specific antigen, Psa, Semenogelase, Seminin,
Immunogen: recombinant protein
Conjugate: Unconjugated
Modification: Unmodified