Product Description

PSD-93 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5868-50, BS5868-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The postsynaptic density protein (PSD)-93 and related membrane associated guanylate kinase (MAGUK) proteins assemble signal transduction complexes at sites of cell-cell contact including synapses. PSD-93 (also designated channel associated protein of synapse-110 or chapsyn-110) occurs only at postsynaptic sites in hippocampal neurons. PSD-95 and PSD-93 mediate ion channel clustering in heterologous cells and are believed to cluster and anchor NMDA receptors at the synapse. The glutamate receptor subunit, delta2, binds specifically to PSD-93, which is enriched in Purkinje neuron cell bodies and dendrites. In addition, PSD-93 clusters delta2 when they are coexpressed and they are colocalized at parallel fiber synapses.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ICC

Alternate Names: Disks large homolog 2, Channel-associated protein of synapse-110, Chapsyn-110, Chapsyn110, Chapsyn 110, Postsynaptic density protein PSD-93, PSD93, DLG2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 647-692 of Human PSD-93.

Dilution: WB: 1:500~1:1000
ICC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PSD-93 polyclonal antibody detects endogenous levels of PSD-93 protein.

Molecular Weight: ~ 110 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15700

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only