Product Description

PSGL-1 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS48581-50, BS48581-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecμles P-, E- and L- selectin expressed on myeloid cells and stimμlated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sμlfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing resμlts in mμltiple transcript variants.[provided by RefSeq, Apr 2011]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC, ICC/IF, FC, IP

Alternate Names: CLA, CD162, PSGL1, PSGL-1

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of human PSGL-1

Dilution: WB: 1:1000 IHC: 1:200 ICC/IF: 1:100 FC: 1:100 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 250 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q14242

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only