Product Description

PSK-H2 Polyclonal Antibody

Catalogue Numbers: BS60060-50, BS60060-100

Sizes: 50µl, 100µl

Alternative Name: Serine/threonine-protein kinase H2; Protein serine kinase H2; PSK-H2; PSKH2

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q96QS6

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB

All Applications: WB: 1:500~1:1000

Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. PSKH2 (protein serine kinase H2) is a 385 amino acid protein belonging to the CAMK Ser/Thr protein kinase family. Containing one protein kinase domain, PSKH2 is encoded by a gene located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PSK-H2 polyclonal antibody detects endogenous levels of PSK-H2 protein.

Bioworld Molecular Weight: ~ 43 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of PSK-H2 polyclonal antibody at 1:500 dilution
Lane 1: Hela whole cell lysate
Lane 2: HEK293T whole cell lysate
Lane 3: Mouse brain tissue lysate

Immunogen: A synthetic peptide corresponding to residues in Human PSK-H2.

Conjugate: Unconjugated

Modification: Unmodified