Product Description

PSMA Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11473-50, MB11473-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q04609

Host: Rabbit

Reactivity: Mouse

Applications: WB

All Applications: WB: 1/500-1/1000

Background: PSMA has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PSMA in 3T3Lysates using PSMA antibody.

Bioworld Molecular Weight: Calculated MW: 84 kDa; Observed MW: 100 kDa

Specificity: IgG

Alternative Name: FGCP; FOLH 1; GCP 2; GCPII; mGCP; NAALADase I; PSM; PSMA

Immunogen: A synthetic peptide of human PSMA

Conjugate: Unconjugated

Modification: Unmodified