Product Description

PSMA Mouse Monoclonal Antibody (1F12)

Sizes: 50μL, 100μL

Catalogue Numbers: RA11903-50, RA11903-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: folate hydrolase 1 (FOLH1) Homo sapiens This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alter

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: IHC

Alternate Names: Glutamate carboxypeptidase 2 (EC 3.4.17.21) (Cell growth-inhibiting gene 27 protein) (Folate hydrolase 1) (Folylpoly-gamma-glutamate carboxypeptidase) (FGCP) (Glutamate carboxypeptidase II) (GCPII) (Membrane glutamate carboxypeptidase) (mGCP) (N-acetylated-alpha-linked acidic dipeptidase I) (NAALADase I) (Prostate-specific membrane antigen) (PSM) (PSMA) (Pteroylpoly-gamma-glutamate carboxypeptidase)

Clonality: Monoclonal

Dilution: IHC 1:50-200

Storage: -20°C/1 year

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.47% sodium azide.

Human Gene ID: 2346

Protein Molecular Weight（KDa): 100

Molecular Weight: 100

Research Use Only