PSMA Mouse Monoclonal Antibody (1F12) - RA11903

PSMA Mouse Monoclonal Antibody (1F12)

Size: 50μL, 100μL

Catalogue Numbers: RA11903-50, RA11903-100

Citations, Manuals and MSDS Available upon request.

Background: folate hydrolase 1 (FOLH1) Homo sapiens This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alter

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.47% sodium azide.

Storage Instructions: -20°C/1 year

Applications: IHC

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 2346

Protein MW (KDa): 100

SWISS: Q04609

Source: Mouse

Research Use Only