Product Description

PSMA1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS91125-50, BS91125-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P25786(Human) Q9R1P4(Mouse) P18420(Rat)

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC FC IP,

All Applications: WB:1:500-1:2,000
IHC:1:50-1:200
FC:1:50-1:100
ICC:1:50-1:200

Background: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).

Purification and Purity: ProA affinity purified

Storage and Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: PSMA1 polyclonal antibody detects endogenous levels of PSMA1 protein.

Bioworld Molecular Weight: 30 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Proteasome 20S C2 on different lysates using anti-Proteasome 20S C2 antibody at 1/500 dilution.
Positive control:
Lane 1: PC-3M
Lane 2: K562
Lane 3: Rat testis
Lane 4: Mouse testis
Lane 5: Mouse colon, Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-Proteasome 20S C2 antibody. Counter stained with hematoxylin.

Alternative Name: PROS-30, PSMA1, HC2, NU, PROS30, PSC2, 30 kDa prosomal protein, HC 2, HC2, Macropain subunit C2, Macropain subunit nu, MGC14542, MGC14575, MGC14751, MGC1667, MGC21459, MGC22853, MGC23915, Multicatalytic endopeptidase complex subunit C2, NU, PROS 30, PROS-30, PROS30, Proteasome (prosome macropain) subunit alpha type 1, Proteasome alpha 1 subunit, Proteasome component C2, Proteasome nu chain, Proteasome subunit alpha type 1, Proteasome subunit alpha type I, Proteasome subunit alpha type-1, Proteasome subunit nu, Protein P30 33K, PSA1, PSC 2, PSC2, PSMA 1, psmA1,

Immunogen: Recombinant protein

Conjugate: Unconjugated

Modification: Unmodified