Product Description

PSMC3IP Polyclonal Antibody

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BS65843-50, BS65843-100

Swiss-Prot: Q9P2W1

Host: Rabbit

PSMC3IP Polyclonal Antibody-BS65843

Storage and Stability: Store at 4°C short term. Aliquot and store at -16°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit,

Applications: IHC-P

All Applications: IHC-P=1:100-500

Background: This gene encodes a protein that functions in meiotic recombination. It is a subunit of the PSMC3IP/MND1 complex, which interacts with PSMC3/TBP1 to stimulate DMC1- and RAD51-mediated strand exchange during meiosis. The protein encoded by this gene can also co-activate ligand-driven transcription mediated by estrogen, androgen, glucocorticoid, progesterone, and thyroid nuclear receptors. Mutations in this gene cause XX female gonadal dysgenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2011]

Purification and Purity: affinity purified by Protein A

Specificity: PSMC3IP Polyclonal Antibody detects endogenous levels of PSMC3IP protein.

Bioworld Molecular Weight: ~24 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Paraformaldehyde-fixed, paraffin embedded (Mouse colon)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PSMC3IP) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C, Paraformaldehyde-fixed, paraffin embedded (Mouse testis)Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PSMC3IP) Polyclonal Antibody, Unconjugated at 1:400 overnight at 4°C

Alternative Name: 26S protease regulatory subunit 6A; 26S proteasome AAA-ATPase subunit RPT5; Human immunodeficiency virus tat transactivator binding protein 1; MGC8487; Proteasome (prosome macropain) 26S subunit ATPase 3; Proteasome 26S ATPase subunit 3; Proteasome 26S subunit ATPase 3; Proteasome subunit P50; PRS6A_HUMAN; PSMC 3; PSMC3; Tat binding protein 1; TAT-binding protein 1; TBP-1; TBP1.

Immunogen: KLH conjugated synthetic peptide derived from human PSMC3IP:1-100/217

Modification: Unmodified

Conjugate: Unconjugated