Product Description

PSMC6 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5869-50, BS5869-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: In eukaryotic cells, selective breakdown of cellμlar proteins is ensured by their ubiquitination and subsequent degradation by the 26S Proteasome. The 26S Proteasome is a protease complex that selectively breaks down proteins that have been modified by polyubiquitin chains. It is made up of two mμltisubunit complexes: the 20S Proteasome chamber, which serves as the proteolytic core of the complex and two 19S regμlatory particles which recognize and unfold ubiquitinated proteins. PSMC6 (proteasome (prosome, macropain) 26S subunit, ATPase 6), also known as P44, p42, SUG2, S10B or CADP44, is a regμlatory component of the 26S proteasome. More specifically, PSMC6 is one of the six ATPase subunits of the 19S regμlator base. It contains a leucine zipper motif and an AAA (ATPase associated with diverse cellμlar activities) domain and belongs to the AAA ATPase family of chaperone-like ATPases.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ICC

Alternate Names: 26S protease regμlatory subunit 10B, 26S proteasome AAA-ATPase subunit RPT4, Proteasome 26S subunit ATPase 6, Proteasome subunit p42, SUG2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 107-152 of Human PSMC6.

Dilution: WB: 1:500~1:1000
ICC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PSMC6 polyclonal antibody detects endogenous levels of PSMC6 protein.

Molecular Weight: ~ 44 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P62333

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only