PSMC6 rabbit pAb - ES3270

PSMC6 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3270-50, ES3270-100

Citations, Manuals and MSDS Available upon request.

Background: proteasome 26S subunit, ATPase 6 (PSMC6) Homo sapiens The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chrom

Alternate Name: PSMC6; SUG2; 26S protease regulatory subunit 10B; 26S proteasome AAA-ATPase subunit RPT4; Proteasome 26S subunit ATPase 6; Proteasome subunit p42

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse

Immunogen: The antiserum was produced against synthesized peptide derived from human PSMC6. AA range:61-110

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 44kD

Human Gene ID: 5706

Human SWISS Prot NO: P62333

Subcellular Location: Cytoplasm. Nucleus.

Research Use Only