Product Description

PSMD3 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS5870-50, BS5870-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: In eukaryotic cells, selective breakdown of cellμlar proteins is ensured by their ubiquitination and subsequent degradation by the 26S Proteasome. The 26S Proteasome is a protease complex that selectively breaks down proteins that have been modified by polyubiquitin chains. It is made up of two mμltisubunit complexes: the 20S Proteasome chamber, which serves as the proteolytic core of the complex and two 19S regμlatory particles which recognize and unfold ubiquitinated proteins. PSMD3 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 3), also known as S3, P58 or RPN3, is a 534 amino acid regμlatory component of the 26S Proteasome that consists of one PCI domain. PSMD3 is encoded by a gene located on human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC

Alternate Names: 26S proteasome non-ATPase regμlatory subunit 3, 26S proteasome regμlatory subunit RPN3, 26S proteasome regμlatory subunit S3, Proteasome subunit p58

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 400-445 of Human PSMD3.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PSMD3 polyclonal antibody detects endogenous levels of PSMD3 protein.

Molecular Weight: ~ 61 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O43242

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only