Product Description

PSTPIP1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS70899-50, BS70899-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O43586

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Background: The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PSTPIP1 polyclonal antibody detects endogenous levels of PSTPIP1 protein.

Bioworld Molecular Weight: ~ 48 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cells, using PSTPIP1 antibody., Immunohistochemistry of paraffin-embedded human gastric using PSTPIP1 antibody at dilution of 1:100 (x40 lens)., Immunohistochemistry of paraffin-embedded mouse kidney using PSTPIP1 antibody at dilution of 1:100 (x40 lens).

Alternative Name: H-PIP; PAPAS; CD2BP1; PSTPIP; CD2BP1L; CD2BP1S;

Immunogen: Recombinant protein of human PSTPIP1.

Conjugate: Unconjugated

Modification: Unmodified