PTBP2 Rabbit Monoclonal Antibody-BS40039

PTBP2 Rabbit Monoclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Sizes: 50µl, 100µl

Catalogue Numbers: BS40039-50, BS40039-100

Swiss-Prot: Q9UKA9

Host: Rabbit

PTBP2 Rabbit Monoclonal Antibody-BS40039

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF

All Applications: WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200

Background: RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.

Purification and Purity: Affinity-chromatography

Specificity: PTBP2 Antibody detects endogenous levels of total PTBP2

Bioworld Molecular Weight: 57kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PTBP2 in (1) Neuro-2a cell lysate; (2) HeLa cell lysate., Immunohistochemical analysis of paraffin-embedded human colon, using PTBP2 Antibody.

Alternative Name: brPTB; MIBP; nPTB; Polypyrimidine tract binding protein 2; PTB like protein; PTBP 2Ptbp2; Splicing regulator;

Immunogen: A synthesized peptide derived from human PTBP2

Modification: Unmodified

Conjugate: Unconjugated