PTH-rP rabbit pAb - ES8508

PTH-rP rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8508-50, ES8508-100

Citations, Manuals and MSDS Available upon request.

Background: parathyroid hormone like hormone (PTHLH) Homo sapiens The protein encoded by this gene is a member of the parathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone. [provided by RefSeq, Nov 2013],

Alternate Name: Parathyroid hormone-related protein (PTH-rP) (PTHrP) (Parathyroid hormone-like protein) (PLP) [Cleaved into: PTHrP[1-36]; PTHrP[38-94]; Osteostatin (PTHrP[107-139])]

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Rat; Mouse;

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PTHLH. AA range:101-150

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 25kD

Human Gene ID: 5744

Human SWISS Prot NO: P12272

Subcellular Location: Cytoplasm. Nucleus. Secreted.

Research Use Only