Product Description

PTK2 (FAK) Mouse Monoclonal Antibody

Sizes: 25μl, 100μl

Catalogue Numbers: MB4370-25, MB4370-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellμlar matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellμlar signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellμlar matrix. Several transcript variants encoding different isoforms have been found for this gene, but the fμll-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: IF, IHC, WB

Alternate Names: FADK, FADK 1, FAK, FAK1, FRNK, p125FAK, pp125FAK, PPP1R71

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Fμll length human recombinant protein of human PTK2(NP_722560) produced in HEK293T cell.

Dilution: WB 1:200~2000, IHC 1:150, IF 1:100

Purification: The antibody was affinity-purified from mouse ascites fluids or tissue cμlture supernatant by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IgG1

Molecular Weight: 119.1 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q05397

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only