Product Description

PTK6 (phospho-Y342) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS64195-50, BS64195-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellμlar signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and resμlts in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing resμlts in mμltiple transcript variants.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: IHC

Alternate Names: Protein-tyrosine kinase 6, Breast tumor kinase, Tyrosine-protein kinase BRK, PTK6, BRK

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylation

Immunogen: Synthetic phosphopeptide derived from human PTK6 around the phosphorylation site of Tyrosine342.

Dilution: IHC: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PTK6 (phospho-Y342) polyclonal antibody detects endogenous levels of PTK6 protein only when phosphorylated at Tyr342.

Molecular Weight: ~ 52kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q13882

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only