Product Description

PTK6 (phospho-Y342) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS64195-50, BS64195-100

Sizes: 50µl, 100µl

Swiss-Prot: Q13882

Host: Rabbit

Reactivity: Human

Applications: IHC

Background: The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PTK6 (phospho-Y342) polyclonal antibody detects endogenous levels of PTK6 protein only when phosphorylated at Tyr342.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of PTK6 (phospho-Y342) polyclonal antibody in paraffin-embedded human stomach cancer tissue at 1:50.

Bioworld Molecular Weight: ~ 52kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Protein-tyrosine kinase 6; Breast tumor kinase; Tyrosine-protein kinase BRK; PTK6; BRK

Immunogen: Synthetic phosphopeptide derived from human PTK6 around the phosphorylation site of Tyrosine342.

Conjugate: Unconjugated

Modification: Phosphorylation