Product Description

PTN Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS7504-50, BS7504-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Pleiotrophin?(PTN) also known as?heparin-binding brain mitogen?(HBBM) or?heparin-binding growth factor 8?(HBGF-8) or?neurite growth-promoting factor 1?(NEGF1) or?heparin affinity regμlatory peptide?(HARP) or?heparin binding growth associated molecμle?(HB-GAM) is a?protein?that in humans is encoded by the?PTNgene.?Pleiotrophin is an 18-kDa?growth factor?that has a high affinity for?heparin. It is structurally related to?midkine?and?retinoic acid induced heparin-binding protein. Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regμlation of cell proliferation.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC

Alternate Names: HARP, HB-GAM, HBBM, HBGAM, HBGF-8, HBGF8, HBNF, HBNF-1, HBNF1, heparin affin regμlatory protein, Heparin binding growth associated molecμle, Heparin Binding Growth Factor 8, Heparin binding neurite outgrowth promoting factor 1, Heparin-binding brain mitogen, heparin-binding growth associated molecμle, Heparin-binding growth factor 8, Heparin-binding growth-associated molecμle, Heparin-binding neurite outgrowth-promoting factor 1, NEGF1, Neurite Growth Promoting Factor 1, Neurite outgrowth-promoting factor, heparin-binding, OSF-1, OSF1, Osteoblast-specific factor 1, osteoblast-specific factor, pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1), Pleiotrophin, PTN, PTN_HUMAN,

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human PTN.

Dilution: WB 1:500 - 1:2000
IHC 1:50 - 1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PTN polyclonal antibody detects endogenous levels of PTN protein.

Molecular Weight: ~19 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P21246

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only