PTP22 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA29097-50, RA29097-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: protein tyrosine phosphatase, non-receptor type 22 (PTPN22) Homo sapiens This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009], Reactivity: Human, Mouse, Rat Host: Rabbit Applications: WB, ELISA Alternate Names: PTPN22, PTPN8, Tyrosine-protein phosphatase non-receptor type 22, Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, Lymphoid phosphatase, LyP, PEST-domain phosphatase, PEP Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Molecular Weight: 91 Protein Molecular Weight (kDa): 91 Storage: -20°C/1 year Human Gene ID: 26191 Human SwissProt Number: Q9Y2R2 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only