PTP22 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA29097-50, RA29097-100 Citations, Manuals and MSDS Available upon request. Background: protein tyrosine phosphatase, non-receptor type 22 (PTPN22) Homo sapiens This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Mar 2009], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications. Alternative Names: PTPN22; PTPN8; Tyrosine-protein phosphatase non-receptor type 22; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; LyP; PEST-domain phosphatase; PEP Applications: WB; ELISA Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 26191 Protein MW (KDa): 91 SWISS: Q9Y2R2 Source: Rabbit Research Use Only