Product Description

PTPN1 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8457-50, BS8457-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The phosphorylation of proteins at tyrosine residues has long been recognized as an important regμlatory component of signal transduction. This is areversible process, involving both enzymes that phosphorylate proteins ontyrosine residues as well as a rapidly expanding family of protein tyrosinephosphatases. These latter enzymes bear little resemblance to either theprotein serine and protein threonine phosphatases or to the acid and alkalinephosphatases. In most tissues, the major PTPase is a vanadate- and molybdate-sensitive protein of approximately 40 kDa molecμlar weight. On the basis of sequence analysis, PTP1B expressed in human placenta exhibits similarities both with the common leukocyte antigen (CD45) and with LAR, ahomolog of the neural adhesion molecμle (NCAM). PTPase 1B is synthesized as a 435 amino acid precursor protein which is cleaved to generate the active 321 amino acid enzyme.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, PTPN1, PTP1B

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human PTPN1.

Dilution: WB: 1:500~1:2000
IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PTPN1 polyclonal antibody detects endogenous levels of PTPN1 protein.

Molecular Weight: ~ 50kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P18031

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only