Product Description

PTPR2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65287-50, BS65287-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: protein tyrosine phosphatase, receptor type N2(PTPRN2) Homo sapiens This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4, 5-diphosphate, and this function may be involved in the regμlation of insμlin secretion. This protein has been identified as an autoantigen in insμlin-dependent diabetes mellitus. Alternative splicing resμlts in mμltiple transcript variants. [provided by RefSeq, Feb 2015]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: PTPRN2, KIAA0387, Receptor-type tyrosine-protein phosphatase N2, R-PTP-N2, Islet cell autoantigen-related protein, IAR, ICAAR, Phogrin

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: The antiserum was produced against synthesized peptide derived from human PTPRN2. AA range:206-255

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity: PTP IA-2β Polyclonal Antibody detects endogenous levels of PTP IA-2β protein.

Molecular Weight: ~ 111 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q92932

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only