PTPR2 Polyclonal Antibody-BS65287

PTPR2 Polyclonal Antibody

Catalogue Numbers: BS65287-50, BS65287-100

Sizes: 50µl, 100µl

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Swiss-Prot: Q92932

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,ELISA

All Applications: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Background: protein tyrosine phosphatase, receptor type N2(PTPRN2) Homo sapiens This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PTP IA-2β Polyclonal Antibody detects endogenous levels of PTP IA-2β protein.

Extra Notes: Western blot analysis of lysates from NIH/3T3 cells, using PTPRN2 Antibody. The lane on the right is blocked with the synthesized peptide.

Bioworld Molecular Weight: ~ 111 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: PTPRN2; KIAA0387; Receptor-type tyrosine-protein phosphatase N2; R-PTP-N2; Islet cell autoantigen-related protein; IAR; ICAAR; Phogrin

Immunogen: The antiserum was produced against synthesized peptide derived from human PTPRN2. AA range:206-255

Conjugate: Unconjugated

Modification: Unmodified