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PTPRG Polyclonal Antibody - E-AB-90767

PTPRG Polyclonal Antibody - E-AB-90767

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PTPRG Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-90767-60, E-AB-90767-120, E-AB-90767-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PTPRG

Target Synonym: PTPRG; HPTPG; PTPG; R-PTP-GAMMA; RPTPG

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P23470

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human PTPRG

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 158kDa/162kDa

Observed MW: 140-162kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

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