Product Description

PTPRK Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS75947-50, BS75947-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecμles that regμlate a variety of cellμlar processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellμlar region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellμlar region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellμlar interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimμlated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation.

Category: Primary Antibody

Reactivity: Mouse

Host: Rabbit

Applications: WB

Alternate Names: PTPRK, R-PTP-kappa

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human PTPRK(NP_001129120.1).

Dilution: WB, 1:500 - 1:2000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Unmodification

Molecular Weight: 162kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q15262

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only