PTPRO Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-92750-60, E-AB-92750-120, E-AB-92750-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PTPRO
Target Synonym: PTPRO; GLEPP1; NPHS6; PTP-OC; PTP-U2; PTPROT; PTPU2; R-PTP-O
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Mouse
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q16827
Background: This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human PTPRO
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 43kDa/47kDa/67kDa/134kDa/138kDa
Observed MW: 138kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only