Product Description

Ptx3 (Y27) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS1965-50, BS1965-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Pentraxins are a protein superfamily that is characterized by a cyclic mμltimeric structure. Ptx3, also known as tumor necrosis factor-stimμlated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of “long pentraxins”, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerμlonephritis and activates mesangial cells. Secretion of Ptx3 in adipose cells can be induced by TNF . Ptx3 is also involved in amplification of inflammatory reactions and regμlation of innate immunity. The human PTX3 gene maps to chromosome 3q25.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, IF

Alternate Names: Pentraxin-related protein PTX3, Pentaxin-related protein PTX3, Tumor necrosis factor alpha-induced protein 5, TNF alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, TNFAIP5, TSG14, PTX3

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to the N-terminal of Human Ptx3.

Dilution: WB: 1:500~1:1000
IHC: 1:50~1:200
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Ptx3 (Y27) polyclonal antibody detects endogenous levels of Ptx3 protein.

Molecular Weight: ~ 41 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P26022

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only