PWWP2B Polyclonal Antibody - BT-AP07514

PWWP2B Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP07514-20, BT-AP07514-50, BT-AP07514-100

Citations, Manuals and MSDS Available upon request.

Background: PWWP2B (PWWP domain containing 2B) is a 590 amino acid protein that contains a PWWP domain which is involved in protein-protein interactions. The PWWP2B protein is phosphorylated upon DNA damage, probably by Atm or ATR. The PWWP2B gene is conserved in chimpanzee, cow, mouse, rat, chicken and zebrafish, and maps to human chromosome 10q26. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4. % of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.

Research Areas: Cell Biology

Target Protein: PWWP2B

Applications: WB, IHC-p, ELISA

Reactivity: Human

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: PWWP2B Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 63967

UniProt Accession: Human: Q6NUJ5

Synonyms: PWWP2B; PWWP2; PWWP domain-containing protein 2B

GeneID: Human: 170394

Research Use Only