Product Description

PYK2 (4B4) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB3142-50, MB3142-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q14289

Host: Mouse

Reactivity: Human

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: PYK2 a nonreceptor tyrosine kinase of the Fak family. Predominantly expressed in the cells derived from hematopoietic lineages and in the central nervous system. PYK2 is one of the signaling mediators for G-protein-coupled receptors. Involved in calcium induced regulation of ion channel and activation of the map kinase signaling pathway. Interacts with the SH2 domain of Grb2.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG2a

Bioworld Molecular Weight: Calculated MW: 116 kDa; Observed MW: 116 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Pyk2 in A549, Ramos, Jurkat, THP-1 and Raji lysates using Pyk2 antibody., Immunohistochemistry analysis of paraffin-embedded Human Tonsil tissues using PYK2 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: PTK2B; FAK2; PYK2; RAFTK; Protein-tyrosine kinase 2-beta; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Pro

Immunogen: Purified recombinant fragment of PYK2 (aa815-997) expressed in E. Coli.

Conjugate: Unconjugated

Modification: Unmodified