Pyruvate Dehydrogenase E1 alpha Monoclonal Antibody-MB12338

Pyruvate Dehydrogenase E1 alpha Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12338-50, MB12338-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P08559

Host: Mouse

Reactivity: Human, Mouse,Monkey,Rat

Applications: WB,ICC/IF

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200

Background: The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). Catalyzes the removal of CO2 from pyruvate. Mutations in the α subunits of pyruvate dehydrogenase (E1) lead to congenital defects that are usually associated with lactic acidosis, neurodegeneration and early death.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of pyruvate dehydrogenase alpha 1 in COS7, Jurkat, C6, 3T3 and HelaLysates using pyruvate dehydrogenase alpha 1 antibody.

Bioworld Molecular Weight: Calculated MW: 43 kDa; Observed MW: 43 kDa

Specificity: IgG1

Alternative Name: mitochondrial; ODPA_HUMAN; PDH; PDHA; PDHA1; PDHCE1A; PDHE1 A type I; PDHE1-A type I; PHE1A; Pyruvate Dehydrogenase (lipoamide) alpha 1; Pyruvate dehydrogenase complex; E1 alpha polypeptide 1; Pyruvate Dehydrogenase E1 alpha; Pyruvate dehydrogenase E1 component subunit alpha; Pyruvate dehydrogenase E1 component subunit alpha; somatic form; mitochondrial; somatic form.

Immunogen: Purified recombinant human Pyruvate Dehydrogenase protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodified