QPCT Polyclonal Antibody-BS8375

QPCT Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Sizes: 50µl, 100µl

Catalogue Numbers: BS8375-50, BS8375-100

Swiss-Prot: Q16769

Host: Rabbit

QPCT Polyclonal Antibody-BS8375

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IF

All Applications: WB: 1:500~1:2000
IF: 1:50~1:200

Background: QPCT (glutaminyl-peptide cyclotransferase) is a 361 amino acid protein that belongs to the glutaminyl-peptide cyclotransferase family. QPCT is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. QPCT binds one zinc ion per subunit and has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue. The human QPCT gene shares 86% overall sequence identity with the bovine homolog. QPCT contains an N-terminal signal peptide region, several glycosylation and phosphorylation sites and two cysteine residues conserved between the bovine and human enzymes. Existing as two alternatively spliced isoforms, the QPCT gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito, M.grisea and N.crassa, and maps to human chromosome 2p22.2.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: QPCT polyclonal antibody detects endogenous levels of QPCT protein.

Bioworld Molecular Weight: ~ 41 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of extracts of various cell lines, using QPCT antibody., Immunofluorescence analysis of MCF-7 cells using QPCT antibody.

Alternative Name: Glutaminyl-peptide cyclotransferase; Glutaminyl cyclase; QC; sQC; Glutaminyl-tRNA cyclotransferase; Glutamyl cyclase; EC; QPCT

Immunogen: Recombinant full length Human QPCT.

Modification: Unmodified

Conjugate: Unconjugated