Product Description

QPCT Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8375-50, BS8375-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: QPCT (glutaminyl-peptide cyclotransferase) is a 361 amino acid protein that belongs to the glutaminyl-peptide cyclotransferase family. QPCT is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. QPCT binds one zinc ion per subunit and has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue. The human QPCT gene shares 86% overall sequence identity with the bovine homolog. QPCT contains an N-terminal signal peptide region, several glycosylation and phosphorylation sites and two cysteine residues conserved between the bovine and human enzymes. Existing as two alternatively spliced isoforms, the QPCT gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, fruit fly, mosquito, M.grisea and N.crassa, and maps to human chromosome 2p22.2.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF

Alternate Names: Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase, QC, sQC, Glutaminyl-tRNA cyclotransferase, Glutamyl cyclase, EC, QPCT

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human QPCT.

Dilution: WB: 1:500~1:2000
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: QPCT polyclonal antibody detects endogenous levels of QPCT protein.

Molecular Weight: ~ 41 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q16769

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only