R4RL2 rabbit pAb - ES11214

R4RL2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES11214-50, ES11214-100

Citations, Manuals and MSDS Available upon request.

Background: function:May play a role in regulating axonal regeneration and plasticity in the adult central nervous system., PTM:Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein., similarity:Belongs to the Nogo receptor family., similarity:Contains 8 LRR (leucine-rich) repeats., subcellular location:Localized to the surface of neurons, including axons., tissue specificity:Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.,

Source: Rabbit

Applications: WB; ELISA

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Reactivity: Human; Rat; Mouse

Immunogen: Synthesized peptide derived from human protein . at AA range: 290-370

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 46kD

Human Gene ID: 349667

Human SWISS Prot NO: Q86UN3

Subcellular Location: Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft. Cell projection, dendrite. Perikaryon. Cell projection, axon. Localized to the surface of neurons, including axons. Detected close to synapses, but is excluded from synapses.

Research Use Only