Rab 38 rabbit pAb - ES5378

Rab 38 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5378-50, ES5378-100

Citations, Manuals and MSDS Available upon request.

Background: function:May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1., PTM:Although at least one in vitro system can process and methylate the prenylated C-terminal, in an in vitro system that normally express Rab-38 and in vivo the prenylated C-terminal is not proteolytically processed and not methylated., similarity:Belongs to the small GTPase superfamily. Rab family., tissue specificity:Expressed in melanocytes.,

Alternate Name: RAB38; Ras-related protein Rab-38; Melanoma antigen NY-MEL-1

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human RAB38. AA range:80-129

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 26kD

Human Gene ID: 23682

Human SWISS Prot NO: P57729

Subcellular Location: Cell membrane; Lipid-anchor; Cytoplasmic side. Melanosome. Cytoplasmic vesicle, phagosome. Cytoplasmic vesicle, phagosome membrane; Lipid-anchor; Cytoplasmic side. Melanosome membrane. Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211). The BLOC-3 complex, a heterodimer of HPS1 and HPS4 promotes its membrane localization (PubMed:23084991).

Research Use Only