Rab 5C (A153) Polyclonal Antibody-BS3919

Rab 5C (A153) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS3919-50, BS3919-100

Sizes: 50µl, 100µl

Swiss-Prot: P51148

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: Rab 5C (A153) polyclonal antibody detects endogenous levels of Rab 5C protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of Rab 5C (A153) pAb at 1:1000 dilution
Lane 1: A375 whole cell lysate (40ug)
Lane 2: Hela whole cell lysate (30ug)
Lane 3: The Lung tissue lysate of Rat (40ug)
Lane 4: The Lung tissue lysate of Mouse (40ug), Immunohistochemistry (IHC) analyzes of Rab 5C (A153) pAb in paraffin-embedded human colorectal carcinoma tissue at 1:50.

Bioworld Molecular Weight: ~ 24 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: RAB; member of RAS oncogene family like;
RAB5C;
RAB5C; member of RAS oncogene family;
RAB5C; member RAS oncogene family;
RAB5C;
RAB5CL;
RAB5L;
RABL;
Ras-related protein Rab-5C;

Immunogen: Synthetic peptide, corresponding to amino acids 130-180 of Human Rab 5C.

Conjugate: Unconjugated

Modification: Unmodified