RAB14 Polyclonal Antibody
Catalogue Numbers: BS60444-50, BS60444-100
Sizes: 50µl, 100µl
Alternative Name: Ras-related protein Rab-14; RAB14
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P61106
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB
All Applications: WB: 1:500~1:1000
Background: The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 14, also known as FBP, is a 215 amino acid protein that is lipid-anchored to the cytoplasmic side of the cell membrane. One of several members of the Rab subfamily of small GTPases, Rab 14 is thought to be involved in vesicular trafficking and neurotransmitter release throughout the body and is expressed at high levels in brain, lung, kidney, spleen and thymus.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: RAB14 polyclonal antibody detects endogenous levels of RAB14 protein.
Bioworld Molecular Weight: ~ 22 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of RAB14 polyclonal antibody at 1:500 dilution
Lane 1: Jurkat whole cell lysate
Lane 2: Raw264.7 whole cell lysate
Lane 3: PC12 whole cell lysate
Immunogen: A synthetic peptide corresponding to residues in Human RAB14.
Conjugate: Unconjugated
Modification: Unmodified