RAB18 Monoclonal Antibody-MB67217

RAB18 Monoclonal Antibody

Catalogue Numbers: MB67217-50, MB67217-100

Sizes: 50µl, 100µl

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: Q9NP72

Host: Mouse

Reactivity: Human, Mouse, Rat

Applications: WB, FC

All Applications: WB (1/500 - 1/1000), FC (1/10 - 1/50)

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the localization of ZFYVE1 to lipid droplets and for its function in mediating the formation of endoplasmic reticulum-lipid droplets (ER-LD) contacts. Also required for maintaining endoplasmic reticulum structure. Plays a role in apical endocytosis/recycling (By similarity). Plays a key role in eye and brain development and neurodegeneration.

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of RAB18 protein.

Extra Notes: Western blot analysis of RAB18 expression in PC3 (A), mouse brain (B), rat brain (C), human brain (D), human testis (E) whole cell lysates.

Bioworld Molecular Weight: ~ 25 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Ras-related protein Rab-18

Immunogen: Recombinant fusion protein of human RAB18. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified