Product Description

RAB18 Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB67217-50, MB67217-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The small GTPases Rab are key regμlators of intracellμlar membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the localization of ZFYVE1 to lipid droplets and for its function in mediating the formation of endoplasmic reticμlum-lipid droplets (ER-LD) contacts. Also required for maintaining endoplasmic reticμlum structure. Plays a role in apical endocytosis/recycling (By similarity). Plays a key role in eye and brain development and neurodegeneration.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: WB, FC

Alternate Names: Ras-related protein Rab-18

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fusion protein of human RAB18. The exact sequence is proprietary.

Dilution: WB (1/500 - 1/1000), FC (1/10 - 1/50)

Purification: This antibody is purified through a protein G column.

Specificity: Recognizes endogenous levels of RAB18 protein.

Molecular Weight: ~ 25 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NP72

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Research Use Only