RAB1B Monoclonal Antibody-MB67201

RAB1B Monoclonal Antibody

Catalogue Numbers: MB67201-50, MB67201-100

Sizes: 50µl, 100µl

Product: Mouse IgG1 kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: Q9H0U4

Host: Mouse

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB (1/1000 - 1/2000)

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Plays a role in the initial events of the autophagic vacuole development which take place at specialized regions of the endoplasmic reticulum. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments (By similarity). Required to modulate the compacted morphology of the Golgi. Promotes the recruitment of lipid phosphatase MTMR6 to the endoplasmic reticulum-Golgi intermediate compartment (By similarity).

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of RAB1B protein.

Extra Notes: Western blot analysis of RAB1B expression in Hela (A), A431 (B), U20S (C), rat liver (D), NIH3T3 (E) whole cell lysates.

Bioworld Molecular Weight: ~ 26 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Ras-related protein Rab-1B

Immunogen: Recombinant fusion protein of human RAB1B. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified