Product Description

RAB20 Polyclonal Antibody

Catalogue Numbers: BS62456-50, BS62456-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.4.

Swiss-Prot: Q9NX57

Host: Rabbit

Reactivity: Human, Rat, Mouse

Applications: WB IHC

All Applications: WB:1:500~1:1000 IHC:1:50~1:200

Background: The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies all of which are thought to play an important role in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 20 (Ras-related protein Rab-20) is a 234 amino acid protein that localizes to the golgi apparatus and belongs to the Rab subfamily of small GTPases. Expressed in normal and cancerous pancreatic tissue, Rab 20 plays an important role in apical endocytosis and recycling and may be involved in the development of exocrine pancreatic adenocarcinomas.

Purification and Purity: The protein was purified from E.coli and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -25°C long term. Avoid freeze-thaw cycles.

Specificity: RAB20 polyclonal antibody detects endogenous levels of RAB20 protein.

Extra Notes: Western blot (WB) analysis of RAB20 polyclonal antibody at 1:500 dilution
LaneA:Hela whole cell lysate
LaneB:H1792 whole cell lysate
LaneC:BV2 whole cell lysate
LaneD:MEF whole cell lysate
LaneE:C6 whole cell lysate

Bioworld Molecular Weight: ~ 26 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Ras-related protein Rab-20; RAB20

Immunogen: Synthetic peptide, corresponding to Human RAB20.

Conjugate: Unconjugated

Modification: Unmodified