RAB21 Monoclonal Antibody-MB67246

RAB21 Monoclonal Antibody

Catalogue Numbers: MB67246-50, MB67246-100

Sizes: 50µl, 100µl

Product: Mouse IgG2b kappa. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: Q9UL25

Host: Mouse

Reactivity: Human, Monkey

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Small GTPase involved in membrane trafficking control. During the mitosis of adherent cells, controls the endosomal trafficking of integrins which is required for the successful completion of cytokinesis. Regulates integrin internalization and recycling, but does not influence the traffic of endosomally translocated receptors in general (By similarity). As a result, may regulate cell adhesion and migration (By similarity). Involved in neurite growth (By similarity). Following SBF2/MTMT13-mediated activation in response to starvation-induced autophagy, binds to and regulates SNARE protein VAMP8 endolysosomal transport required for SNARE-mediated autophagosome-lysosome fusion. Modulates protein levels of the cargo receptors TMED2 and TMED10, and required for appropriate Golgi localization of TMED10.

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of RAB21 protein.

Extra Notes: Western blot analysis of RAB21 expression in MCF7 (A), A431 (B), Hela (C), COS7 (D) whole cell lysates.

Bioworld Molecular Weight: ~ 24 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: KIAA0118; Ras-related protein Rab-21

Immunogen: Recombinant fusion protein of human RAB21. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified