Rab5 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11494-50, MB11494-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P20339
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100
Background: Rab5 is a member of the Ras superfamily of small Rab GTPases. Rab5 is localized at the plasma membrane and early endosomes and functions as a key regulator of vesicular trafficking during early endocytosis (1). The conformational change between Rab5 GTP/GDP states is essential for its biological function as a rate limiting regulator at multiple steps during endocytosis.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 24 kDa; Observed MW: 24 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Rab5 in K562, C6, 3T3, Hela lysates using Rab5 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Rab5 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.
Alternative Name: RAB5A; RAB5; RAS associated protein RAB5A; Ras related protein Rab 5A
Immunogen: A synthetic peptide of human Rab5
Conjugate: Unconjugated
Modification: Unmodified