Product Description

Rab5 Polyclonal Antibody

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16636-50, BZ16636-100

Swiss-Prot: P20339

Host: Rabbit

Rab5 Polyclonal Antibody-BZ16636

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: Rab5 is a member of the Ras superfamily of small Rab GTPases. Rab5 is localized at the plasma membrane and early endosomes and functions as a key regulator of vesicular trafficking during early endocytosis (1). The conformational change between Rab5 GTP/GDP states is essential for its biological function as a rate limiting regulator at multiple steps during endocytosis.

Purification and Purity: Affinity Purified

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 24 kDa; Observed MW: 24 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Rab5 in MCF-7Lysates using Rab5 antibody., Immunohistochemistry analysis of paraffin-embedded Human colon using Rab5 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: RAB5A; RAB5; RAS associated protein RAB5A; Ras related protein Rab 5A

Immunogen: A synthesized peptide derived from human Rab5

Modification: Unmodified

Conjugate: Unconjugated