Product Description

RAB5C Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS8846-50, BS8846-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P51148

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

All Applications: WB: 1:500~1:2000
IHC: 1:50~1:200

Background: The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RAB5C polyclonal antibody detects endogenous levels of RAB5C protein.

Bioworld Molecular Weight: ~ 23kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western Blot analysis of extracts of various cell lines, using RAB5C antibody.

Alternative Name: RAB; member of RAS oncogene family like;
RAB5C;
RAB5C; member of RAS oncogene family;
RAB5C; member RAS oncogene family;
RAB5C;
RAB5CL;
RAB5L;
RABL;
Ras-related protein Rab-5C;

Immunogen: Recombinant full length Human RAB5C.

Conjugate: Unconjugated

Modification: Unmodified