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RAB6A Polyclonal Antibody - E-AB-12261

RAB6A Polyclonal Antibody - E-AB-12261

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RAB6A Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-12261-60, E-AB-12261-120, E-AB-12261-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: RAB6A

Target Synonym: GTP binding protein RAB6A'; GTP binding protein RAB6B; Oncogene RAB6; Rab 6; Rab GTPase; Rab-6; RAB6; RAB6 member RAS oncogene family; RAB6A; RAB6A member RAS oncogene family; Rab6A variant 3; RAB6A'; RAB6A; RAB6B; Ras related protein Rab 6A; Ras-related protein Rab-6A; RCO4 3

Research Areas: Cancer, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P20340

Background: This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Concentration: 0.4 mg/mL

Immunogen: Synthetic peptide of human RAB6A

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 24kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only