RAB7L1 Polyclonal Antibody-BS5879

RAB7L1 Polyclonal Antibody

Catalogue Numbers: BS5879-50, BS5879-100

Sizes: 50µl, 100µl

Alternative Name: Ras-related protein Rab-7L1; Rab-7-like protein 1; RAB-7L1

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: O14966

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: The Ras-related superfamily of guanine nucleotide binding proteins includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies. Increasing data suggests an important role for Rab proteins in either endocytosis or in biosynthetic protein transport. The process of transporting newly synthesized proteins from the endoplasmic reticulum (ER) to various stacks of the Golgi complex and to secretory vesicles involves the movement of carrier vesicles and requires Rab protein function. Rab proteins are also an integral part of endocytic pathways. Rab 7L1, also known as RAB7L, is a 203 amino acid, ubiquitously expressed member of the Rab family of proteins that localizes to the cell membrane. Rab 7L1 contains four GTP-binding domains and shares 35% identity with Rab 7 and 94% identity with the rat protein Rab 29. In addition, Rab 7L1 is often used as a marker of T cells.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: RAB7L1 polyclonal antibody detects endogenous levels of RAB7L1 protein.

Bioworld Molecular Weight: ~ 23 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of RAB7L1 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T cell lysate
Lane 2: sp2/0 cell lysate
Lane 3: PC12 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 156-201 of Human RAB7L1.

Conjugate: Unconjugated

Modification: Unmodified